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Whether they persist or resolve with continued use is not yet fully characterised from long-term data

Leg Cramp Causes In a study of people aged 60 years and older, almost 1/3 experienced leg cramps in the previous 2 months, including half of those 80 and older

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The subjects who, at that time, switched from semaglutide 2.4mg to placebo had regained half of that weight after 48 weeks, whereas those who continued on active treatment achieved an additional weight loss of around 8% in the same time period