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Vitamin B 12 is essential for metabolism, energy production and red blood cells.

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Rangel-Zuiga, Ana Leon-Acua, Mara M

Increased the expression of p-Akt, HO-1 and Nrf2 with compared with pre-treatment for 2 h with LY294002 (a PI3K inhibitor) in PC12 cells

Increased vitamin C intake is associated with elevated BMD at the hip and lumbar spine (56), and a diet high in vitamin C demonstrates a significant reduction in hip fracture risk (57)