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Therefore, targeting the PGE2-EP2/EP4 signaling axis might offer a promising avenue for the reduction of Th17 cells in psoriasis patients, positioning it as a prospective therapeutic strategy

the leucine-rich repeat kinase 2 (LRRK2) protein induces ferroptosis by acting on the System Xc/GSH/GPX4 pathway (51) and the m6A demethylase fat mass and obesity-associated protein can promote ferroptosis via the p53/SLC7A11 axis (39)

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